Lab Key visual

Welcome to LCSO! Our group is driven by the passion of discovering new reactivity in organic chemistry, especially using catalysis. Basing on high energy molecules, such as strained rings or cyclic hypervalent iodine reagents for electrophilic alkynylation and other transformations, we develop non-conventional bond disconnections for the synthesis of important building blocks and bioactive molecules. Regular group meetings and seminars allow us to share and enhance our knowledge and love of organic chemistry.


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latest news

October 11: Raphael Simonet-Davin successfully passed his PhD candidacy exam. Well done!

October 8: Ashis Das successfully passed his PhD candidacy exam. Well done!

October 7: Julien Borrel from CPE Lyon has received an ISIC Master Grant to join LCSO on February 2019. Congratulation!

October 1: LCSO has received a grant of the Swiss National Science Foundation to support his research on “Exploiting Strained Bonds for Innovative Chemical Synthesis”.

September 24: Raphael Simonet-Davin was selected for an oral presentation at the Ischia Summer School. Congratulation!

September 21: Phill Greenwood has won a poster prize at ICOS. Congratulation!

September 18: Nina Declas and Eliott Le Du are now starting their PhD in the group.

September 15 : Our work about the safety profile of ABX as azidation reagent and safer alternatives is now published in J. Org. Chem. (DOI: 10.1021/acs.joc.8b02068). It has been selected by the editors for ACS for open access! (ACS Etitor’s Choice)

September 10: Mingming Wang successfully passed his PhD candidacy exam. Well done!

September 7: Marion Garreau has won a runner up prize for her poster at the Swiss Chemical Society Fall Meeting. Congratulation!

August 21 : The work of Paola and Raj on the metal-free coupling of Indole-BX reagents with electron-rich heteroarenes has been highlighted by Timothy Swager and Martin Peeks in the journal Synfacts. (DOI: 10.1055/s-0037-1610510)

August 9 : Our first pre-print at ChemRxiv   about the safety profile of ABX as azidation reagent and safer alternatives is now online! (DOI: 10.26434/chemrxiv.6946058.v1)

July 16: The LCSO group outing  2018 has taken place: sailing on the lake of Geneva!

July 12: The cover page for our recent article on photoredox mediated fragmentation-alkynylation of cyclic oxime ethers designed together with Anya from the Corminboeuf group is now online in Chemical Science .

July 9: The teaching website of LCSO has been updated, including the first English version of the Asymmetric Synthesis bachelor course.

July 9: Our comprehensive overview on alkynylations and vinylations using hypervalent iodine reagents is now available in Patai.

July 4: Stefano Nicolai received the award for the best poster presentation at the 6th International Conference on Hypervalent Iodine Chemistry in Cardiff. Congratulations!

June 7: Daniele Perrotta received a SNF postdoctoral fellowship to join the group of Chris Vanderwal at UC Irvine. Congratulations!

June 6: Our recent work on fine-tuned organic photoredox catalysts for fragmentation-alkynylation cascades has been selected as hot article by (Chemical Science).

May 30: The last results of Franck Le Vaillant , Marion Garreau and Stefano Nicolai on organic dyes for photoredox mediated fragmentation-alkynylation cascades with computation performed by Ganna Gryn’ova in the Corminboeuf group have been accepted for publication in Chemical Science (DOI: 10.1039/C8SC01818A).

May 25: The last results of Erwann Grenet, Ashis Das and Paola Caramenti on the Rhodium-catalyzed C–H functionalization of heteroarenes using indoleBX have been published in Beilstein Journal of Organic Chemistry (DOI: 10.3762/bjoc.14.102 ).

May 4: The last results of Paola Caramenti and Raj Nandi on the metal-free coupling of indoles with electron-rich arenes have been accepted for publication in Chemistry- A European Journal (DOI: 10.1002/chem.201802142).

May 4: Daniele Perrotta successfully defended his PhD thesis. He is the tenth PhD student to obtain his degree at LCSO. Congratulations!

April 25: Durga Hari leaves LCSO after four years of highly successful postdoc. He will now join the Aggarwal group at the University of Bristol. Good luck Durga!

April 23: Paola Caramenti and Franck Le Vailant received a SCS-SCNAT Travel Award to go to the BOSS and ICHIC conferences respectively. Congratulations!

April 5: Daniele Perrotta successfully passed his PhD exam in front of an impressive jury composed of Prof. Jieping Zhu, Nicolai Cramer, Daniel Werz and Paolo Melchiorre. Congratulations!

March 5: The work of Franck Le Vaillant on decarboxylative cyanation/alkynylation maide it into the most downloaded articles in Chemical Science!

February 23: The work of Daniele Perrotta has been further highlighted on the faculty website and several news portals, such as Science Daily.

February 21: The last results of Erwann Grenet on the C-H heteroarylation of benzaldehydes with IndoleBX reagents have been published in Organic Letters (DOI: 10.1021/acs.orglett.8b00337).

February 20: The last work of Daniele Perrotta and Ming-Ming Wang on the enantioselective desymmetrization of Donor-Acceptor Cyclopropanes has been accepted in Angewandte Chemie (DOI: 10.1002/anie.201800494).

February 9Guillaume Pisella successfully passed his PhD candidacy. Congratulation!!!

February 1Nina Declas joins the group for a Master internship. Welcome and good luck!

January 15: Stephanie Amos is now starting her PhD. Welcome back at LCSO!